Long URL generating 400 error

I have a URL that is defined as the src property of a script on my home page. The URL contains 1037 characters total. Most of that is one query string. That query string can be variable length, and if I delete most of it, the script works fine.

If I leave the long URL as is, I get nothing. In Chrome's Inspect Element Console window, I get the following error for the URL:

Failed to load resource: the server responded with a status of 400 (Bad Request)

In my web.config for the site, I have the following:

<httpRuntime maxUrlLength="4096" maxQueryStringLength="4096" />

The system hosting the site is running Windows Server 2008 R2 and IIS7.

Any suggestions for what is causing the error? Thanks!